At an oral dose of 2000 mg/kg/working day in rats, maternal toxicity and deaths have been observed with an increased incidence of early fetal resorption; spontaneous abortions happened in cynomolgus monkeys with the maternally toxic oral dose of 2000 mg/kg/working day; there won't be any sufficient and well-managed trials in https://paule443qcn6.losblogos.com/profile