[4] Molecular and pharmacological components of piperine as a possible molecule for disease prevention and management: evidence from medical trials "We confirmed that conolidine binds towards the freshly identified opioid receptor ACKR3, although demonstrating no affinity for the other 4 classical opioid receptors. By doing so, conolidine blocks ACKR3 https://what-is-chronic-pain00864.dailyblogzz.com/31520013/rumored-buzz-on-conolidine