The key consideration for plasmid purification is separation of plasmid DNA from the chromosomal DNA and cellular RNA from the host bacteria. A number of approaches are already developed to crank out a cleared lysate that not just take out protein and lipids, and also proficiently eliminate contaminating chromosomal DNA https://devinlmljg.empirewiki.com/8358740/small_dna_fragment_extraction_and_purification_fundamentals_explained